Risk prediction for invasive candidiasis
نویسندگان
چکیده
منابع مشابه
Epidemiology and risk factors for invasive candidiasis
The number of immunosuppressive patients has increased significantly in recent years. These patients are at risk for opportunistic infections, especially fungal infections. Candidiasis is one of the most frequent fungal infections determined in these immunosuppressive patients and its epidemiology has changed over the last two decades. Recently, new antifungal agents and new therapy strategies ...
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Invasive fungal infections (IFIs) are among the life-threatening issues in patients with impaired immune system. High administration of antifungals in these patients imposes a heavy economic burden on the national health system. In addition, despite the usually expensive antifungal regimens, the mortality rate due to fungal infections is still high, resulting in the loss of hundreds of lives pe...
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See the article by Blumberg et al. on pages 177–86. For 3 decades, systemic antifungal use was virtually a 1-drug act—amphotericin B. Administration of antifungal agents to critically ill patients was dominated by fear of toxicity rather than knowledge of its efficacy. In the past decade, the availability of azole antifungal agents with enhanced pharmacokinetic and safety profiles completely re...
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Invasive candidiasis is a major source of morbidity and mortality in critically ill patients. The creation and validation of clinical prediction rules to identify patients at high risk has given clinicians access to advanced management strategies, such as targeted prophylaxis, pre-emptive therapy, and protocolized empirical therapy.
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BACKGROUND Anidulafungin, a new echinocandin, has potent activity against candida species. We compared anidulafungin with fluconazole in a randomized, double-blind, noninferiority trial of treatment for invasive candidiasis. METHODS Adults with invasive candidiasis were randomly assigned to receive either intravenous anidulafungin or intravenous fluconazole. All patients could receive oral fl...
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ژورنال
عنوان ژورنال: Indian Journal of Critical Care Medicine
سال: 2014
ISSN: 0972-5229,1998-359X
DOI: 10.4103/0972-5229.142178